The researchers observed the behavior of mice, which seemed lazier than their counterparts. Scientists concluded: everything comes from a lack of a gene that is responsible for protein synthesis, which regulates the energy balance of the cell. Experts have voiced the assumption that the nature of human laziness is exactly the same.
Scientists from the Canadian McMaster University published the results of their research in the journal Proceedings of the National Academy of Sciences. A population of rodents lacking certain genes was bred. These same genes control the production of the AMPK enzyme, which, being activated with a significant consumption of cell energy, transfers it into an "energy-saving" state. The behavior of mice that lacked these genes was markedly different from the behavior of ordinary, active and loving mice.
The bred mice did not differ at all from the usual ones in appearance, but turned out to be less mobile. It turned out that they have fewer mitochondria - internal "power plants" that synthesize the energy source of the cell ATP, and their muscle tissue absorbs glucose worse.
For the first time, scientists have shown the relationship between AMPK, mitochondrial function and physical activity, said Gregory Steinberg, head of the study. The results of the study will help to understand those who like to be lazy and those who find it difficult to provide themselves with the necessary level of physical activity (for example, asthmatics).